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1

Does co-aggregation of the CD45 and CD3 antigens inhibit T cell antigen receptor complex-mediated activation of phospholipase C and protein kinase C?

Emer Shivnan, Mark Biffen, Masahiro Shiroo, Edward Pratt, Martin Glennie, Denis Alexander

Journal:

European Journal of Immunology

Année:

1992

Langue:

english

Fichier:

PDF, 999 KB

english, 1992

2

Selective coupling of the T cell antigen receptor to phosphoinositide-derived diacylglycerol production in HPB-ALL T cells correlates with CD45-regulated p59fyn activity

Mark Biffen, Masahiro Shiroo, Denis R. Alexander

Journal:

European Journal of Immunology

Année:

1993

Langue:

english

Fichier:

PDF, 1.05 MB

english, 1993

3

The role of CD45 in T-cell activation — resolving the paradoxes?

Denis Alexander, Masahiro Shiroo, Anne Robinson, Mark Biffen, Emer Shivnan

Journal:

Immunology Today

Année:

1992

Langue:

english

Fichier:

PDF, 512 KB

english, 1992

4

Inhibition of PI-kinase in rat liver membranes by F−

Mark Biffen, B.Richard Martin

Journal:

Cellular Signalling

Année:

1989

Langue:

english

Fichier:

PDF, 390 KB

english, 1989

5

Purification and characterization of recombinant rat mast cell protease 7 expressed in Pichia pastoris

Carolyn Lawson, Craig Walker, James Awford, Mark Biffen, Philip Mallinder, Andrew Jackson

Journal:

Protein Expression and Purification

Année:

2002

Langue:

english

Fichier:

PDF, 174 KB

english, 2002

6

Polyphosphoinositidase activity in soybean membranes is Ca2+-dependent and shows no requirement for guanine-nucleotides

Mark Biffen, David E. Hanke

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 684 KB

english, 1990

7

Metabolic fate of myo-inositol in soybean callus cells

Mark Biffen, David E. Hanke

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 863 KB

english, 1991

8

Haemophilus influenzae Induces Neutrophil Necrosis

Naylor, Emma J., Bakstad, Denise, Biffen, Mark, Thong, Bob, Calverley, Peter, Scott, Stephen, Hart, C. Anthony, Moots, Robert J., Edwards, Steven W.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2007

9

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] C33. ANTI-INFLAMMATORY STRATEGIES IN AIRWAYS DISEASE: ANIMAL MODELS - Biological Activity Of Novel TLR7 Ante-drug Agonists For The Treatment Of Allergic Diseases

Biffen, Mark, Matsui, Hiroyuki, Edwards, Susan, Satterthwaite, Gemma, Doyle, Ian, Holness, Elain, Leishman, Andrew, Eiho, Kazuo, Aoki, Masamitsu, Tomizawa, Hideyuki, Takaku, Haruo, Murray, Clare

Année:

2010

Langue:

english

Fichier:

PDF, 17 KB

english, 2010

10

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] D35. MODULATORS OF AIRWAY INFLAMMATION - AZD8848/DSP-3025 Is A Novel Potent TLR7 Agonist Ante-Drug That Demonstrates Negligible Systemic Activity And A Prolonged Period Of Control After Cessation Of Weekly Dosing In A Brown Norway Rat Ovalbumin Challenge Model

Bell, John P., Britt, Jim, Biffen, Mark, Ferguson, Douglas, Aoki, Mikio, Eiho, Kazuo, Bahl, Ashwani K., Takaku, Haruo, Murray, Clare

Année:

2010

Langue:

english

Fichier:

PDF, 18 KB

english, 2010

11

Temporal cytokine and lymphoid responses to an inhaled TLR7 antedrug agonist in the cynomolgus monkey demonstrates potential safety and tolerability of this approach

Bell, John, Dymond, Mike, Biffen, Mark, Delaney, Stephen, Keeling, David, Zhang, Hui, Robinson, Ian

Journal:

Toxicology and Applied Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2018